Hanan Alarnous
Biomedical engineering
Hometown: Al-khobar, Eastern Province, Saudi Arabia
Graduation date: Spring 2024
Additional details: First-generation college student
MORE | Spring 2024
Development of Biomimetic Nanoparticles for Smooth Muscle Dysfunction
Atherosclerosis remains a global factor in mortality and morbidity. As the disease progresses, plaque builds up within the arterial wall narrowing the lumen. Interventions such as angioplasty and stenting cause vascular injury which induces pathological phenotypes in smooth muscle cells (SMC), leading to neointima hyperplasia. This project addresses the challenge by developing a biomimetic nanodrug to inhibit the SMC pathology. It focuses on characterizing the physicochemical properties of the nanoparticles and evaluating their efficacy in suppressing SMC dysfunction. Successful completion of this project could pave the way for future in-vivo testing of the nano-drug in mitigating arterial stenosis following interventions.
Mentor: Kuei-Chun (Mark) Wang
It’s hip to be square.
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Sponsored project | Spring 2024
Hanan Alarnous’ MORE project is sponsored by W. L. Gore & Associates.
W. L. Gore & Associates is a uniquely creative, product leadership enterprise that has served a variety of global markets for more than 60 years, and provides innovative solutions that its associates stand behind. Gore established funds to support undergraduate students in the Fulton Undergraduate Research Initiative program and graduate students in the Master’s Opportunity for Research in Engineering program, and values student-driven research and developing relationships with students in the programs.