FURI | Spring 2022

Using 3D Printing to Develop a Placenta-on-a-Chip Model

Placental trophoblasts support fetal growth and survival, but the behavior of these cells is challenging to study in vivo and in two-dimensional culture systems. In this project, we investigate the use of 3D printing to generate an on-a-chip platform to study trophoblast behavior. We evaluated the feasibility of printing the chips on glass slides and optimized chip design printing with clear resin. Future studies will investigate the feasibility of trophoblast culture and analysis on the fabricated chip.