Ashley H. Tse
Hometown: Phoenix, Arizona, United States
Graduation date: Spring 2023
FURI | Fall 2021
Engineering of Light-Based Promoters with PACE and eVOLVER Continuous Culture Hardware
Phage-assisted continuous evolution (PACE) is a revolutionary new method to rapidly engineer new genes and proteins, but the method requires extensive automation and expensive chemical inducers for precise control of gene expression. The researcher is developing an advanced method of synthetic gene regulation for process control, using optogenetics. By integrating light-based gene circuits with custom hardware for directed evolution, optogenetics allows for precise fine-tuning of PACE for versatile and scalable applications.
Mentor: Benjamin Bartelle
Sponsored project | Fall 2021
W. L. Gore & Associates is a uniquely creative, product leadership enterprise that has served a variety of global markets for 60 years, and provides innovative solutions that its associates stand behind. Gore established funds to support undergraduate students in the Fulton Undergraduate Research Initiative program and graduate students in the Master’s Opportunity for Research in Engineering program, and values student-driven research and developing relationships with students in the programs.