Irien Bobby
Biomedical engineering
Hometown: Idukki, Kerala, IN
Graduation date: Spring 2028
Additional details: Honors student
FURI | Fall 2026, Needs Review
Optimizing Electrospinning Parameters for Nanofiber Scaffold Fabrication for Regenerative Medicine
The aim of this project is to understand how the physicochemical properties of electrospun polycaprolactone (PCL) nanofiber scaffolds affect their use in regenerative medicine, with the focus being polymer concentration, flow rate, distance between syringe output and target, and voltage applied. These variables will be studied using a design of experiments (DOE) approach. To compare scaffolds produced under different conditions, the fiber diameter, pore size and fiber morphology will be analyzed by optical and possibly scanning electron microscopy (SEM) and ImageJ analysis. By understanding the conditions that produce reproducible scaffold structures, the production of biomaterials that provide improved growth and regeneration conditions for cells can be improved. Future studies will evaluate the scaffolds for cell attachment, viability and proliferation in order to determine their potential to be used in regenerative medicine applications.
Mentor: Vincent Pizziconi
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