Alondra Davila
Biomedical engineering
Hometown: Mesa, Arizona, United States
Graduation date: Spring 2025
Additional details: First-generation college student
FURI | Fall 2024
Characterization of Diclofenac-Loaded Nanoparticles for Neutrophil Modulation
Traumatic brain injury (TBI) can lead to long-term disability and even death. Developing effective therapies is imperative to improving the quality of life for TBI patients. The permeability of the blood-brain barrier after TBI allows for enhanced delivery of therapeutics. Nanoparticles (NPs) are a promising drug delivery system as their physicochemical properties can be tuned for brain delivery. Diclofenac — an anti-inflammatory drug — can be encapsulated in NPs to reduce neutrophil infiltration into the injured brain by decreasing L-selectin expression. In this study, the effect of diclofenac-loaded NPs in comparison to free diclofenac on L-selectin shedding will be characterized in vitro.
Mentor: Sarah Stabenfeldt
It’s hip to be square.
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Sponsored project | Fall 2024
Alondra Davila’s FURI project is sponsored by the Ahmad Family Fulton Undergraduate Research Initiative Fund.
Jalal U. and Syeda F. Ahmad and their children — Jaheen N., Raisa N. and Nafisah N., all of whom attended the Fulton Schools — established a fund to give back and support undergraduate students in their pursuit of knowledge and the advancement of research. Their endowment, which funds a materials science, mechanical, biomedical or electrical engineering student, was created to help more students have the life-changing experience of conducting research through FURI.