Meaghan Eilis D'Arcy
Biomedical engineering
Hometown: Phoenix, Arizona, United States
Graduation date: Spring 2025
Additional details: Honors student
FURI | Fall 2024
Preparation of 3D in vitro Models with Predictable Oxygen Distribution
This research aims to develop a 3D in vitro model for measuring tissue oxygenation and predicting its distribution. The imaging will be done using a novel MRI technique developed in the ProBE lab, PISTOL (Proton Imaging of Siloxanes to map Tissue Oxygenation Levels). An oxygen-sensitive 3D scaffold will simulate pO2 profiles under different conditions. The model allows for the analysis of tissue oxygenation at hypoxic and normoxic levels to study cellular response to varying oxygen levels. This research provides insight into hypoxia-related diseases and advancements in MRI-compatible biomedical devices, with potential applications in improving treatments for conditions like cancer and stroke.
Mentor: Vikram Kodibagkar
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