Krishna Ramana Mohan Sai Bonda
Biomedical engineering
Hometown: Oakland Township, Michigan, US
Graduation date: Spring 2026
FURI | Fall 2026, Needs Review
Developing a Standard Operating Procedure for Magnetic Resonance Electrical Impedance Tomography(MREIT) of Neurons
A 2019 CDC survey found that 39% of US adults experienced back pain within the previous three months [1]. Neuromodulation therapies targeting the dorsal root ganglia (DRG), which relay pain signals, require surgical implantation, and no targeted, portable option exists for managing flare-ups at home. Developing such devices requires understanding how DRG neurons fire, yet there is limited research published that discusses how to measure their activity. Magnetic Resonance Electrical Impedance Tomography (MREIT) uses MRI and injected currents to map tissue conductivity, which may change when neurons fire. This project aims to develop a standard operating procedure for MREIT imaging of DRG neurons. The research team has developed 3D printed an MRI-compatible phantom chambers and established a collagen hydrogel to house the neurons. Future work will finalize current injection and acquire scans to model DRG activity and guide at-home therapy design.
Mentor: Rosalind Sadleir
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