FURI | Fall 2019

Synthesis of Calcium Phosphate Nanoparticles with the Inclusion of Metabolites and Ovalbumin

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Cancer is a life-threatening disease that involves uncontrolled cell growth. This project aims to inhibit glucose metabolism that feeds the cancer cells and cause the cells to proliferate by using a glycolytic inhibitor, PFK15. Moreover, a novel combination of calcium phosphate nanoparticles that contain specific metabolites will be synthesized to further modify the glycolytic pathway. The manipulation of glucose production will ideally result in the killing of melanoma (skin cancer) cells while keeping normal cells alive. A significant step aiding in curing melanoma will benefit the quality of life of people affected by this illness.