FURI | Spring 2021

panCanSYGNAL

Health icon, disabled. A red heart with a cardiac rhythm running through it.

A web application has been developed to provide data and statistics for comprehensive gene regulatory network of the deadly cancer malignant pleural mesothelioma (MPM). The web application was enhanced to include additional experimental information from CRISPR-Cas9 knock-out outgrowth screens. The ultimate goal of the website is to function as a hypothesis knowledge base and hypothesis generator for researchers that study MPM. This required additional graphics and information to be displayed in efficient ways, and led to changes in the database structure and web application. Future plans include expanding the website to cover 32 additional cancers characterized by The Cancer Genome Atlas.

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