FURI | Fall 2019

Engineering High Yield Production of L-Serine in Cyanobacteria

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Cyanobacteria have the potential to efficiently produce L-serine, an industrially important amino acid, directly from CO2 and sunlight, which is a more sustainable and cheaper source of energy as compared to current methods. The research aims to maximize the production of L-serine in a metabolically engineered strain of cyanobacteria by optimizing the expression levels of the serA and serine exporter genes, optimizing the growth conditions, and investigating the effects of nitrogen supplementation. The L-serine levels will be tracked using gas chromatography. The work can be extended by the deletion of genes that are involved in the amino acid’s degradation.

Student researcher

Omar Abed

Omar Abed

Chemical engineering

Hometown: Maricopa, Arizona, United States

Graduation date: Spring 2020