FURI | Summer 2020

Assessment of Injury Induced Blood Brain Barrier Disruption and Necroptosis via Development of Rapid Data Analysis Pipeline

The goal of the project completed by the researcher was to establish a Java program that aids in the efficiency and accuracy of traumatic brain injury (TBI) scan analysis. Current modes of completing analysis were time consuming and imprecise. Precision tools involving individual pixel analysis were implemented to optimize the program for Horseradish Peroxidase staining (HRP) and Immunofluorescence staining (IFC), while allowing it to be expanded to include additional stain options. This project established a mode of TBI image analysis through an accessible user interface (UI), adaptable editor options, and the ability to store the crucial data with ease.